Technology
LinkSēq™ | Accurate, Fast, Easy HLA Typing
LinkSēq™ is a new sequence-specific priming (SSP) chemistry that is analyzed using real-time PCR platforms (click here). This innovative chemistry, an end-point PCR process, uses SYBR® Green to detect HLA amplification. Rather than separating DNA based on size, as in gel electrophoresis, melt curves identify specific DNA based on melting temperature (Tm). As double stranded DNA melts, SYBR® Green is released into solution, which causes a change in fluorescence. This change is recorded as a "melt curve". Once the PCR amplification process is completed, a melt curve analysis is performed to identify specific HLA alleles. SureTyper™ software identifies the HLA type by comparing the pattern of positive and negative reactions to known HLA sequences, simplifying the genotyping process.
Products
HLA-ABDR (10 tests each)
HLA-AB (10 tests each)
HLA-ADR (10 tests each)
HLA-A (20 tests each)
HLA-B (10 tests each)
HLA-DR (20 tests each)
HLA-DQ and HLA-C Coming Soon!
Contact the sales department for the latest information.
*Linkage Biosciences™ and LinkSēq™ are trademarks of Linkage Biosciences Inc. SYBR® is a registered trademark of Life Technologies Corporation. This product line is covered by issued and pending patents worldwide. For Research Use Only. Not intended for any animal or human therapeutic or diagnostic, unless otherwise stated.